Researchers from the Albert Einstein College of Medicine have discovered that ageing in mouse is regulated by cell in the hypothalamus , the structure find in vertebrates ' brains that operate metabolism and growth .

In theirNature newspaper , the team establish   that hypothalamic stem cell are least partly responsible for for how fast the aging process occurs . The number of these cells begins to fall when the rats are 10 calendar month one-time , which is considerably earlier than when the first visible signs of aging appear . By 24 calendar month , when the mice were very old , most of these mobile phone were live .

" Our research shows that the number of hypothalamic neuronic theme cells naturally declines over the life of the beast , and this declivity accelerates aging , " older source Professor Dongsheng Cai tell in astatement . " But we also find that the core of this deprivation are not irreversible . By replenishing these stem cells or the atom they produce , it ’s potential to slow and even reverse various aspects of aging throughout the soundbox . "

The hypothalamic stem cell release microRNA corpuscle into the cerebrospinal fluid of beast . Unlike stock RNA corpuscle that   are crucial to the synthesis of protein , the microRNA ’s function looks like the ordinance of gene expression .

The scientists took a chemical group of halfway - aged mouse and disrupted the hypothalamic stem cell in their brains . The interrupt mice began aging faster than regular mouse . " This disruption greatly speed up age compared with control mouse , and those animals with disrupted stem cells died earlier than normal , " add Dr Cai .

The team also wondered if the hypothalamic fore cell could be used in reverse to slow down the aging outgrowth . The researchers injected microRNA extract from the hypothalamic fore cell into the cerebrospinal fluid of the ascendance mice and the middle - aged mice whose hypothalamus had been   disrupted . maturate in both groups was witness to slow down , which was evaluate by assessing   coordination , muscle endurance , social behavior , and cognitive ability .

Researchers are now looking into precisely how the microRNA molecules help oneself to press the aging operation and if this can be translated to human race . Apart from an manifest youth elixir , these molecules could be polar to struggle long time - related degenerative disease .