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Scientists find the strongest grounds yet that the coronavirus SARS - CoV-2 leapt from animal to humans at a food market inChina , fuel thefirst reported outbreak of COVID-19 . The genetic data was uploaded to a public database and then promptly removed at the request of the Chinese team that first share it .
An external squad of scientists reported that swab samples taken in and around the stalls at Huanan Seafood Wholesale Market in early 2020 check SARS - CoV-2 genetic sequence commingled with the DNA of common racoon dogs ( Nyctereutes procyonoides).The Atlanticfirst reported the findings on Friday ( March 17 ) . Raccoon dogs , a fox relative with dark blotches around their eyes , are known to be capable to carry and transmit the coronavirus , The New York Times cover .
The common raccoon dog is an animal related to foxes.
sacrifice when and how the swab samples were collected , and the fact that the computer virus ca n’t persist indefinitely in the surroundings without a host , the analysis intimate that racoon dogs infected with SARS - CoV-2 may have shake off infective virus while they were being lawlessly merchandise at the market in December 2019 , the team concluded .
The analysis , which is not yet gross and has not yet been published , can not in spades prove that septic raccoon dogs were present at the market . And if the beast were infected , the research can not show how they caught the virus or how the virus spread from there .
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However , the bearing of SARS - CoV-2 and raccoon dog transmitted material in the accurate same swob samples at least intimate that septic wild animals were at the market , and thus , had the potential to pass around the computer virus , the scientists said .
" This is a really impregnable indication that animal at the market were infected,“Angela Rasmussen , a virologist involved in the inquiry , tell The Atlantic . " There ’s really no other account that makes any sense . "
The newly - analyzed genetic episode were upload earlier this month to GISAID , an open - access genomic database , by researchers affiliate with China ’s Center for Disease Control and Prevention ( CDC ) , grant to The Atlantic . Evolutionary biologistFlorence Débarrespotted that the raw sequence information had been shared and alerted other research worker .
Just hour after downloading the data from GISAID , scientists led byKristian Andersen , Edward Holmes , andMichael Worobeyuncovered the racoon dog DNA commingled with SARS - CoV-2 genic cloth . The squad show their findings Tuesday ( March 14 ) to the World Health Organization ’s ( WHO ) Scientific Advisory Group for the Origins of Novel Pathogens , The Atlantic report .
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Back in February 2020 , the Chinese CDC research worker had analyzed the same data but write only part of it , making no quotation of raccoon dog DNA . In a preprint , they reportedfinding an " abundance " ofHomo sapienDNAassociated with SARS - CoV-2 , which they enjoin suggested infected humans channel the virus into the market . They could n’t find any grounds pointing to an animal host in that data , they wrote . But graphs in the same preprint contradicted that claim , showinganimal DNA had been plant mixed up with SARS - CoV-2 , Science first reported in 2022 .
short after Tuesday ’s WHO coming together , the Chinese research group ’s 2020 preprint went into review at a compeer - review Nature Research diary , suggesting a new version will soon be put out .
The team that presented their findings to the WHO initially give out to the Chinese investigator to cooperate on the research , but shortly after they made contact , the genetical sequence were removed from GISAID , The New York Times reported .
GISAID noted that the sequences were removed at the request of the submitter , Science describe . When require why the sequence were n’t share sooner , the former head of the China CDC George Gao told Science that the data was " [ n]othing new . It had been known there was illegal animal dealing and this is why the market was at once shut out down . " When asked why GISAID took down the sequence data point , Gao did not reply , but indicated that the data point did not decide thequestion of SARS - CoV-2 ’s origin , which he say is " still scientific and undecided . "
Critics of the widely - support spillover hypothesis — that SARS - CoV-2 leap out from animals to humans — may ultimately want more conclusive evidence than research can offer , Joel Wertheim , an evolutionary biologist involved in the psychoanalysis , told Science .
" You ca n’t observe the zoonotic transmission of a new virus from animate being to humans , " he pronounce . " We ’re just never go to get that level of data point . "
